Material Safety Data
Sheet
Methyl Red Indicator Solution
ACC# 45435
Section 1 - Chemical Product and Company
Identification |
MSDS Name: Methyl Red Indicator
Solution
Catalog Numbers: S71419, S71420
Synonyms: Methyl Red in Alcohol
Company
Identification:
Fisher
Scientific
1 Reagent
Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For
International CHEMTREC assistance, call: 703-527-3887
Section 2 -
Composition, Information on Ingredients |
CAS# |
Chemical Name |
Percent |
EINECS/ELINCS |
67-63-0 |
Isopropyl alcohol |
99.98 |
200-661-7 |
493-52-7 |
Methyl red |
0.02 |
207-776-1 |
Section 3 - Hazards
Identification |
EMERGENCY OVERVIEW
Appearance: colorless liquid. Flash Point: 12.8 deg
C.
Warning! Flammable
liquid and vapor. Causes eye and skin irritation. Prolonged or repeated
contact causes defatting of the skin with irritation, dryness, and cracking. May
cause respiratory and digestive tract irritation. May cause central nervous
system depression. May form explosive peroxides. May cause kidney damage.
Target Organs: Kidneys, central nervous system.
Potential Health Effects
Eye: Produces irritation, characterized by a burning
sensation, redness, tearing, inflammation, and possible corneal injury.
Skin: May cause skin sensitization, an allergic reaction,
which becomes evident upon re-exposure to this material. Prolonged and/or
repeated contact may cause defatting of the skin and dermatitis. May cause
irritation with pain and stinging, especially if the skin is abraded.
Ingestion: May cause gastrointestinal irritation with
nausea, vomiting and diarrhea. May cause kidney damage. May cause central
nervous system depression, characterized by excitement, followed by headache,
dizziness, drowsiness, and nausea. Advanced stages may cause collapse,
unconsciousness, coma and possible death due to respiratory failure.
Inhalation: Inhalation of high concentrations may cause
central nervous system effects characterized by nausea, headache, dizziness,
unconsciousness and coma. Inhalation of vapor may cause respiratory tract
irritation.
Chronic: Prolonged or repeated skin contact may
cause defatting and dermatitis. May cause allergic skin reaction in some
Section 4 - First Aid
Measures |
Eyes: Immediately flush eyes with plenty of water
for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get
medical aid imme diately.
Skin: Get medical aid if
irritation develops or persists. Flush skin with plenty of soap and water.
Ingestion: If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an unconscious person.
Get medical aid immediately.
Inhalation: Get medical aid
immediately. Remove from exposure and move to fresh air immediately. If not
breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Urine acetone test may be helpful in
diagnosis.
Antidote: None reported
Section 5 - Fire
Fighting Measures |
General
Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Vapors can travel to a source of ignition and flash back. Use water spray
to keep fire-exposed containers cool. Containers may explode in the heat of a
fire. This chemical poses an explosion hazard. May form explosive peroxides.
Vapors may be heavier than air. They can spread along the ground and collect in
low or confined areas.
Extinguishing Media: For small
fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam.
Use water spray to cool fire-exposed containers. Water may be ineffective.
Flash Point: 12.8 deg C ( 55.04 deg F)
Autoignition
Temperature: 432.2 deg C ( 809.96 deg F)
Explosion Limits,
Lower:2.5 at 26.1°C
Upper: 12.1 at 65.6°C
NFPA
Rating: (estimated) Health: ; Flammability: ; Instability:
Section 6 -
Accidental Release Measures |
General
Information: Use proper personal protective equipment as indicated in
Section 8.
Spills/Leaks: Absorb spill with inert material
(e.g. vermiculite, sand or earth), then place in suitable container. Remove all
sources of ignition.
Section 7 - Handling
and Storage |
Handling: Wash thoroughly after handling. Remove
contaminated clothing and wash before reuse. Use with adequate ventilation. Use
spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin,
and clothing. Empty containers retain product residue, (liquid and/or vapor),
and can be dangerous. Keep container tightly closed. Avoid ingestion and
inhalation. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose
empty containers to heat, sparks or open flames.
Storage:
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Keep
from contact with oxidizing materials. Store in a cool, dry, well-ventilated
area away from incompatible substances.
Section 8 - Exposure
Controls, Personal Protection |
Engineering
Controls: Use adequate general or local exhaust ventilation to keep
airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name |
ACGIH |
NIOSH |
OSHA -
Final PELs |
Isopropyl alcohol |
200 ppm TWA; 400 ppm STEL |
400 ppm TWA; 980 mg/m3 TWA 2000 ppm IDLH |
400 ppm TWA; 980 mg/m3 TWA |
Methyl red |
none listed |
none listed |
none listed
|
OSHA Vacated PELs: Isopropyl
alcohol: 400 ppm TWA; 980 mg/m3 TWA Methyl red: No OSHA Vacated PELs are listed
for this chemical.
Personal Protective Equipment
Eyes: Wear safety glasses and chemical goggles if splashing
is possible.
Skin: Wear appropriate gloves to prevent skin
exposure.
Clothing: Wear appropriate protective clothing to
minimize contact with skin.
Respirators: A NIOSH/MSHA approved or
European Standard EN 149 air purifying respirator with an organic vapor
cartridge or canister may be permissible under certain circumstances where
airborne concentrations are expected. A respiratory protection program that
meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN
149 must be followed whenever workplace conditions warrant respirator use.
Section 9 - Physical
and Chemical Properties |
Physical State:
Liquid
Appearance: colorless
Odor: Alcohol odor.
pH: Not available.
Vapor Pressure: 33 mm Hg
Vapor
Density: 2.1 (air=1)
Evaporation Rate:1.5 (n-butyl acetate=1)
Viscosity: 2.1 cP at 25 deg C
Boiling Point: 82 deg C
Freezing/Melting Point:-90 deg C
Decomposition
Temperature:Not available.
Solubility: Completely soluble in
water.
Specific Gravity/Density:0.78 (water=1)
Molecular
Formula:Mixture
Molecular Weight:Not available.
Section 10 -
Stability and Reactivity |
Chemical
Stability: Stable. This material may be sensitive to peroxide formation.
Conditions to Avoid: This material may be sensitive to peroxide
formation., incompatible materials, ignition sources.
Incompatibilities
with Other Materials: Strong oxidizers, acetaldeyde, chlorine, ethylene
oxide, acids and isocyanates, hydrogen + palladium, nitroform, oleum, phosgene,
potassium t-butoxide, oxygen, trinitromethane, barium perchlorate,
tetrafluoroborate, chromium trioxide, sodium dichromate + sulfuric acid,
aluminum, and aluminum triisopropoxide. Isopropyl alcohol has been reported to
be susceptible to autoxidation and should therefore be considered peroxidizable.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide,
acrid smoke and fumes.
Hazardous Polymerization: Has not been
reported.
Section 11 -
Toxicological Information |
RTECS#:
CAS# 67-63-0: NT8050000
CAS# 493-52-7: DG8960000
LD50/LC50:
CAS# 67-63-0:
Draize
test, rabbit, eye: 100 mg Severe;
Draize test,
rabbit, eye: 10 mg Moderate;
Draize test,
rabbit, eye: 100 mg/24H Moderate;
Draize test,
rabbit, skin: 500 mg Mild;
Inhalation, mouse:
LC50 = 53000 mg/m3;
Inhalation, rat: LC50 =
16000 ppm/8H;
Inhalation, rat: LC50 = 72600
mg/m3;
Oral, mouse: LD50 = 3600
mg/kg;
Oral, mouse: LD50 = 3600
mg/kg;
Oral, rabbit: LD50 = 6410
mg/kg;
Oral, rat: LD50 = 5045
mg/kg;
Oral, rat: LD50 = 5000
mg/kg;
Skin, rabbit: LD50 = 12800
CAS#
493-52-7:
.
Carcinogenicity:
CAS# 67-63-0: Not listed by
ACGIH, IARC, NTP, or CA Prop 65.
CAS# 493-52-7: Not listed by ACGIH, IARC,
NTP, or CA Prop 65.
Epidemiology: Early epidemiological studies
suggested an association between the strong acid manufacture of isopropyl
alcohol and paranasal sinus cancer in workers. The risk of laryngeal cancer may
also be increased in these workers. However, it has not been tested adequately
in animals to assess its carcinogenicity.
Teratogenicity: No data
available.
Reproductive Effects: No data available.
Mutagenicity: No data available.
Neurotoxicity: No data
available.
Other Studies:
Section 12 -
Ecological Information |
Ecotoxicity: No
data available. Isopropanol: Acute aquatic effects: Fathead minnow: LC50 =1000
mg/L/96 Hr. Golden orfe: LC50 = 8970 mg/L/48 Hr. goldfish: LC50 = GT5000 mg/L/24
Hr.
Environmental: Isopropanol has a low potential to affect aquatic
organisms, secondary waste treatment microorganisms, and the germination and
growth of some plants. It is readily biodegradable and is not expected to
persist in an aquatic environment. It is not likely to bioconcentrate.
Physical: None
Other: None
Section 13 - Disposal
Considerations |
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 -
Transport Information |
|
US
DOT |
Canada
TDG |
Shipping Name: |
ISOPROPANOL |
ISOPROPANOL |
Hazard Class: |
3 |
3 |
UN Number: |
UN1219 |
UN1219 |
Packing Group: |
II |
II |
Additional Info: |
|
FLASHPOINT 12 C |
|
Section 15 -
Regulatory Information |
US
FEDERAL
TSCA
CAS#
67-63-0 is listed on the TSCA inventory.
CAS#
493-52-7 is listed on the TSCA inventory.
Health & Safety Reporting
List
CAS# 67-63-0: Effective 12/15/86,
Sunset 12/15/96
Chemical Test
Rules
CAS# 67-63-0: 40 CFR 799.2325
Section 12b
None of the chemicals
are listed under TSCA Section 12b.
TSCA Significant New Use
Rule
None of the chemicals in this material
have a SNUR under TSCA.
CERCLA Hazardous Substances and corresponding
RQs
None of the chemicals in this material
have an RQ.
SARA Section 302 Extremely Hazardous
Substances
None of the chemicals in this
product have a TPQ.
SARA Codes
CAS #
67-63-0: immediate, delayed, fire.
Section 313
This material contains Isopropyl alcohol (CAS#
67-63-0, 99.98%),which is subject to the reporting requirements of Section 313
of SARA Title III and 40 CFR Part 373.
Clean Air
Act:
This material does not contain any
hazardous air pollutants.
This material does
not contain any Class 1 Ozone depletors.
This
material does not contain any Class 2 Ozone depletors.
Clean Water
Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA.
None of the chemicals in this product are
listed as Priority Pollutants under the CWA.
None of the chemicals in this product are
listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this
product are considered highly hazardous by OSHA.
STATE
CAS# 67-63-0 can be found on
the following state right to know lists: California, New Jersey, Pennsylvania,
Minnesota, Massachusetts.
CAS# 493-52-7 is not
present on state lists from CA, PA, MN, MA, FL, or NJ.
California
Prop 65
California No Significant Risk Level: None of the chemicals
in this product are listed.
European/International
Regulations
European Labeling in Accordance with EC
Directives
Hazard Symbols:
Not
available.
Risk Phrases:
Safety Phrases:
WGK
(Water Danger/Protection)
CAS# 67-63-0: 1
CAS# 493-52-7: 2
Canada -
DSL/NDSL
CAS# 67-63-0 is listed on Canada's
DSL List.
CAS# 493-52-7 is listed on Canada's
DSL List.
Canada - WHMIS
This
product has a WHMIS classification of B2, D2B.
This product has been
classified in accordance with the hazard criteria of the Controlled Products
Regulations and the MSDS contains all of the information required by those
regulations.
Canadian Ingredient Disclosure
List
CAS# 67-63-0 is listed on the Canadian
Ingredient Disclosure List.
Section 16 -
Additional Information |
MSDS Creation Date:
10/16/1997
Revision #5 Date: 10/30/2007
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
the suitability of the information for their particular purposes. In no event
shall Fisher be liable for any claims, losses, or damages of any third party or
for lost profits or any special, indirect, incidental, consequential or
exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.